New treatments could turn advanced prostate cancer into a ‘chronic disease’ instead of a death sentence
Many people with advanced prostate cancer are experiencing longer life expectancy thanks to new treatments, according to leading prostate cancer doctors. While these treatments may not always provide a cure, they are transforming a disease that was once considered a death sentence into a manageable chronic condition for many patients.
Dr. Laurence Klotz, a urologic oncologist at Sunnybrook Health Sciences Centre in Toronto, explained that patients with metastatic prostate cancer, where the cancer has spread to other parts of the body, are now living approximately twice as long as they did a decade or two ago. This progress marks a significant achievement in the field of cancer treatment.
Although a cure is often not guaranteed, the disease can be controlled for an extended period in many cases. Dr. Klotz emphasized that while some patients can live with metastatic prostate cancer for 10 to 15 years, there are unfortunate instances where the disease progresses rapidly, leading to a shorter life expectancy.
New treatment options, such as androgen receptor pathway inhibitors, have played a crucial role in extending the lives of patients with advanced prostate cancer. These drugs work by blocking the body’s ability to absorb testosterone, a hormone that fuels the growth of prostate cancer cells. By inhibiting this pathway, the drugs effectively slow down the progression of the disease.
Dr. Kim Chi, a medical oncologist and prostate cancer researcher at BC Cancer and the University of British Columbia, highlighted the importance of these advancements in treatment. He explained that while traditional androgen deprivation therapy can be effective initially, the cancer often returns quickly. However, newer drugs that target specific gene mutations associated with prostate cancer offer promising results in prolonging life expectancy.
In addition to medication, lifestyle factors also play a significant role in managing advanced prostate cancer. Thomas Flannery, a prostate cancer survivor, emphasized the importance of maintaining a healthy diet and regular exercise to counteract the side effects of treatment. He follows a Mediterranean diet, limits red meat consumption, and prioritizes physical activity to stay in shape and prevent metabolic issues.
Despite living with advanced prostate cancer for over a decade, Flannery remains active and engaged in various activities such as skiing, cycling, and sailing. He has become a patient advocate, supporting others with the disease and working with researchers to improve treatment protocols. His story is a testament to the progress made in the treatment of advanced prostate cancer, offering hope to patients and their families facing similar challenges.
