Linoleic acid in seed oils linked to lower inflammation, diabetes risk

A new study conducted by researchers from the Indiana University School of Public Health-Bloomington has shed some light on the benefits of linoleic acid, a common omega-6 fatty acid found in seed oils. This study comes at a time when seed oils have come under scrutiny due to concerns about their potential negative impact on health.

The researchers found that higher levels of linoleic acid in the blood were associated with lower levels of biomarkers related to cardiometabolic risk, including inflammation. This suggests that linoleic acid may actually help reduce the risk of heart disease and type 2 diabetes, contrary to previous beliefs.

The study, which was presented at NUTRITION 2025, used objective biomarkers instead of relying on self-reported dietary habits, making the findings more reliable. People with higher levels of linoleic acid were found to have lower levels of glucose, insulin, and markers of inflammation, indicating a healthier overall risk profile for heart disease and diabetes.

While the findings are promising, the researchers emphasize the need for further studies to confirm whether increased intake of linoleic acid can indeed reduce the risk of heart attacks, stroke, and type 2 diabetes. They also aim to investigate the impact of specific types of oils in future research.

Registered dietitian Michelle Routhenstein, who specializes in heart disease, supports the findings of the study, noting that seed oils may actually be protective of cardiometabolic health when used in appropriate amounts. She highlights the benefits of linoleic acid in lowering LDL cholesterol and reducing inflammatory markers like CRP.

Despite the positive findings of this study, some experts have cautioned against the use of seed oils. A previous study published in Gut linked plant-based cooking oils to an increased risk of colon cancer. However, dietitians point out limitations in the study and recommend choosing cooking oils wisely.

In conclusion, while seed oils like soybean and corn oil containing linoleic acid may have some health benefits, it is important to use them in moderation. Choosing healthier alternatives like olive oil for cooking and incorporating a variety of oils in the diet can help maintain a balanced and heart-healthy approach to eating. Further research is needed to fully understand the impact of seed oils on overall health.