Multiple sclerosis symptoms reduced with vitamin D in new study

A recent study has shed light on the potential benefits of vitamin D supplementation for individuals at risk of developing multiple sclerosis (MS). Previous research has suggested a link between vitamin D deficiency and an increased risk of MS, a chronic autoimmune disease that affects the central nervous system. The new study, conducted in France, focused on adults who had experienced clinically isolated syndrome (CIS), an initial phase of neurological symptoms that may progress to MS.

The study involved 303 participants who were randomly assigned to two groups. One group received high doses of cholecalciferol (vitamin D3) every two weeks for a period of 24 months, while the other group received a placebo. The results showed that 60.3% of the participants who received vitamin D supplementation experienced a relapse of symptoms or new lesions in MRI scans, compared to 74.1% of those who received the placebo. This difference was deemed statistically significant by the researchers.

The findings of the study, which was published in the journal JAMA, suggest that high-dose vitamin D supplementation may help reduce disease activity in individuals with CIS and early stages of MS. The researchers noted that further investigation is needed to explore the potential role of high-dose vitamin D as an additional therapy for MS.

Bruce Bebo, executive vice president of research at the National MS Society, commented on the study, describing it as well-designed and promising. He highlighted that previous studies on vitamin D supplementation and MS have yielded mixed results, with lower doses showing limited effectiveness. Bebo emphasized the importance of high doses of vitamin D and early intervention for individuals with MS.

While the American Academy of Neurology recommends a daily intake of vitamin D ranging from 300 to 4,000 units for adults, the study used a significantly higher dose of 100,000 units every two weeks. Bebo cautioned that excessive intake of vitamin D can have adverse effects, including toxicity and potential kidney damage. He advised individuals with MS to consult with their healthcare provider before starting any vitamin D supplementation regimen.

In conclusion, the study’s findings suggest that high-dose vitamin D supplementation may hold promise for individuals at risk of developing MS. Further research is needed to confirm these results and determine the optimal dosage and timing of vitamin D supplementation for individuals with MS. It is essential for individuals with MS to work closely with their healthcare provider to ensure safe and effective use of vitamin D supplements.