Obesity-related cancers more likely for men with specific body fat measurement

A new study suggests that a larger waist circumference is a more significant risk factor for obesity-related cancers than body mass index (BMI) in men, but not in women. The research, led by Dr. Ming Sun, Dr. Josef Fritz, and Dr. Tanja Stocks from Lund University in Sweden, analyzed data from 340,000 Swedish individuals to explore the relationship between waist circumference, BMI, and cancer risk.
Over a 14-year period, the researchers found that an increase in waist circumference of around 11 cm in men was associated with a 25% higher risk of obesity-related cancers, compared to a 19% increased risk with an elevated BMI. For women, both an increase in waist circumference and BMI by approximately 12 cm were linked to a 13% greater risk of cancer.
The study identified obesity-related cancers, including those affecting the oesophagus, stomach, colon, liver, breast, endometrium, ovaries, and more. The researchers highlighted that waist circumference is a more accurate measure of visceral fat, which is metabolically active and linked to adverse health outcomes like insulin resistance and inflammation.
The gender differences in cancer risk factors were attributed to the way men and women store fat. Men tend to accumulate more visceral fat around the abdomen, while women typically store subcutaneous fat in the hips and thighs. This distinction makes waist circumference a stronger predictor of cancer risk in men than in women.
Dr. Marc Siegel, a clinical professor of medicine at NYU Langone Health, emphasized that BMI is a good indicator of obesity but may not fully capture the inflammatory effects of belly fat, which can contribute to cancer development. Dr. Brett Osborn, a Florida neurosurgeon and longevity expert, echoed this sentiment, highlighting the metabolic toxicity of visceral fat and the importance of measuring waist circumference for men.
To reduce cancer risk, Osborn recommended monitoring waist circumference, engaging in strength training to reduce visceral fat, and maintaining a healthy diet. He emphasized that belly fat is not just a cosmetic concern but a significant risk factor for cancer. Proper nutrition and exercise are crucial in minimizing cancer risk and overall health.
In conclusion, the study underscores the importance of considering waist circumference as a key indicator of cancer risk, especially in men. By understanding the impact of fat distribution on health outcomes, individuals can take proactive steps to reduce their risk of obesity-related cancers and improve their overall well-being.