Despite viral videos, methylene blue won’t improve your mood or cognition, experts say

Methylene blue, a chemical first synthesized in the 1800s as a textiles dye, has gained popularity on social media as a potential mood booster and cognitive enhancer. However, experts caution that its true value lies in treating specific medical conditions, particularly methemoglobinemia, a rare blood disorder.
The recent circulation of a video showing U.S. Health and Human Services Secretary Robert F. Kennedy Jr. adding methylene blue to a glass of water has sparked interest in the compound. Health and wellness influencers, including podcasters like Joe Rogan, have suggested that oral consumption of methylene blue can improve cognition, reduce signs of aging, and even combat cancer. Despite these claims, experts emphasize that methylene blue should only be used under the guidance of a medical professional.
Originally developed as a textiles dye, methylene blue gained recognition for its ability to stain and kill microbes under a microscope. It was later repurposed as a treatment for malaria due to its cost-effectiveness compared to quinine. Today, methylene blue is primarily used to treat methemoglobinemia, a condition where the blood is unable to carry oxygen properly.
Although some social media claims suggest that methylene blue can prevent or treat Alzheimer’s disease, research shows mixed results. While methylene blue has shown promise in untangling tau proteins associated with Alzheimer’s, oral consumption of the compound has not proven effective. Derivatives of methylene blue have shown potential in slowing Alzheimer’s progression, but further research is needed to confirm these findings.
Individuals taking selective serotonin reuptake inhibitors (SSRIs) for depression should avoid methylene blue, as combining the two can lead to serotonin toxicity. Serotonin syndrome can cause various symptoms, including changes in heart rate, blood pressure, body temperature, and muscle function.
The proliferation of health misinformation, including claims about methylene blue, is often attributed to poor scientific literacy among social media users. Experts highlight the importance of understanding the underlying science before spreading information online. Public figures, such as Robert F. Kennedy Jr., are also criticized for contributing to the spread of misinformation without a proper understanding of scientific principles.
In conclusion, while methylene blue has valuable medical applications, it should be used judiciously and under medical supervision. Research on its potential cognitive benefits and Alzheimer’s treatment is ongoing, emphasizing the need for further studies to determine its efficacy and safety. As with any health-related information, it is essential to consult with healthcare professionals before using methylene blue for non-medical purposes.