Anorexia is normally treated with therapy. Now a Canadian team is trying the gut
Anorexia nervosa is a serious and potentially life-threatening eating disorder that primarily affects women and girls. It is characterized by an intense preoccupation with weight loss and a distorted body image. While traditional treatments such as family-based therapy have been effective for some individuals, there is a significant portion of patients who do not respond well to these interventions.
In an effort to explore new treatment options for anorexia, Canadian researchers at McMaster University in Hamilton, Ontario, are conducting a groundbreaking clinical trial involving fecal transplants. Fecal microbial transplants involve transferring beneficial bacteria from a healthy donor to the recipient in order to alter the microbiome in the gut.
Dr. Jennifer Couturier, a child psychiatrist and associate professor of psychiatry at McMaster University, is leading the trial, which will include 20 adolescent females diagnosed with anorexia. Participants will receive oral capsules containing concentrated beneficial bacteria, in addition to standard family-based therapy. The goal is to stabilize nutrition and prevent the harmful effects of starvation.
One of the key reasons why researchers are optimistic about the potential benefits of fecal transplants for anorexia is the malleability of the gut microbiome in children and teens. Studies have shown that gut microbes can influence brain function through the gut-brain axis, highlighting the importance of the connection between the gut and the brain in mental health.
By tracking participants’ weight, mood, and changes in the microbiome, researchers hope to gain insights into the potential therapeutic effects of fecal transplants for anorexia. The ultimate goal is to provide a novel and effective treatment option for individuals struggling with this complex and challenging eating disorder.
In addition to exploring new treatment modalities like fecal transplants, experts emphasize the importance of taking a holistic approach to treating anorexia. This includes considering the metabolic underpinnings of the disorder, as well as addressing co-occurring conditions such as suicidal thoughts, substance use, and trauma.
Overall, the research being conducted at McMaster University represents a significant step forward in the understanding and treatment of anorexia nervosa. By leveraging the gut-brain connection and exploring innovative interventions, researchers are paving the way for improved outcomes and better quality of life for individuals affected by this debilitating disorder.
